Neurofibrillary tangles and Neuritic plaques on Alzheimers Computer Vision Project
Neurofibrillary tangles and neuritic plaques in Alzheimers
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Neuritic plaque
Neurofibrillary tangle
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Description
In this project task, I will accurately train Roboflow using the object detection model to detect neurofibrillary tangles (NFTs) and neuritic plaques (NPs) in histopathology images as pathological hallmark features of neurodegenerative diseases, such as in Alzheimer's disease.
- NFTs can be seen as "flame-shaped" where the cytoskeletal filaments grouped together. The tau protein is inappropriately hyperphosphorylated and clustered into filaments. Also known as “ghost tangles," they are seen as dense bundles that develop on the cell surface of affected neurons, signifying neuronal loss and disintegration.
- NPs are deposits of neuron fragments surrounding a core of amyloid β-protein. These plaques have dystrohic dilated and tortuous neurites, microglia, and surrounding reactive astrocytes. NPs are most numerous in the cerebral cortex and hippocampus.
Images used would be by silver staining, with the commonly used Bielschowsky, Gallyas, and/or Bodian stains. The magnification utilized will be 400x and 600x.
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LICENSE
CC BY 4.0 If you use this dataset in a research paper, please cite it using the following BibTeX:
@misc{
neurofibrillary-tangles-and-neuritic-plaques-on-alzheimers_dataset,
title = { Neurofibrillary tangles and Neuritic plaques on Alzheimers Dataset },
type = { Open Source Dataset },
author = { Neurofibrillary tangles and neuritic plaques in Alzheimers },
howpublished = { \url{ https://universe.roboflow.com/neurofibrillary-tangles-and-neuritic-plaques-in-alzheimers/neurofibrillary-tangles-and-neuritic-plaques-on-alzheimers } },
url = { https://universe.roboflow.com/neurofibrillary-tangles-and-neuritic-plaques-in-alzheimers/neurofibrillary-tangles-and-neuritic-plaques-on-alzheimers },
journal = { Roboflow Universe },
publisher = { Roboflow },
year = { 2024 },
month = { may },
note = { visited on 2024-11-13 },
}